Journal
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
Volume 74, Issue 4, Pages 621-641Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/MMBR.00027-10
Keywords
-
Categories
Funding
- National Institutes of Health [2R01 AI053674, 5K02 AI065615, 1R01 AI075191, 1R21 AI088286, 5F30 ES016487-03, 5T32 AI007476-13, F32 AI089068]
Ask authors/readers for more resources
Pseudomonas aeruginosa strains exhibit significant variability in pathogenicity and ecological flexibility. Such interstrain differences reflect the dynamic nature of the P. aeruginosa genome, which is composed of a relatively invariable core genome and a highly variable accessory genome. Here we review the major classes of genetic elements comprising the P. aeruginosa accessory genome and highlight emerging themes in the acquisition and functional importance of these elements. Although the precise phenotypes endowed by the majority of the P. aeruginosa accessory genome have yet to be determined, rapid progress is being made, and a clearer understanding of the role of the P. aeruginosa accessory genome in ecology and infection is emerging.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available