4.2 Article

An H5N1 highly pathogenic avian influenza virus isolated from a local tree sparrow in Indonesia

Journal

MICROBIOLOGY AND IMMUNOLOGY
Volume 55, Issue 9, Pages 666-672

Publisher

WILEY-BLACKWELL
DOI: 10.1111/j.1348-0421.2011.00361.x

Keywords

H5N1; Indonesia; influenza; sparrow

Funding

  1. Global Center of Excellence (G-COE) for Education and Research on Signal Transduction (Japan Science and Technology Agency)
  2. Founding Research Centers for Emerging and Reemerging Infectious Diseases from the Ministries of Education, Culture, Sports, Science, and Technology
  3. Ministry of Health, Labor, and Welfare of Japan
  4. ERATO (Japan Science and Technology Agency)
  5. National Institute of Allergy and Infectious Diseases Public Health

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The isolation of an H5N1 influenza A virus from a tree sparrow (Passer montanus) captured in East Java, Indonesia in 2010 is reported here. Its hemagglutinin and neuraminidase were genetically similar to those of human isolates from 2006-2007 in Indonesia. The finding of a tree sparrow H5N1 virus that possesses genetically similar surface molecules to those of human viruses highlights the importance of monitoring resident wild birds, as well as migratory birds, for pandemic preparedness.

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