Journal
MICROBIOLOGY AND IMMUNOLOGY
Volume 55, Issue 3, Pages 211-216Publisher
WILEY
DOI: 10.1111/j.1348-0421.2010.00303.x
Keywords
open reading frame 5; phylogenetic analysis; porcine reproductive and respiratory syndrome virus; reverse transcription polymerase chain reaction
Categories
Funding
- National Agriculture and Food Research Organization
- Ministry of Agriculture, Forestry and Fisheries of Japan
Ask authors/readers for more resources
In recent years, no reports regarding genetic information on porcine reproductive and respiratory syndrome virus (PRRSV) with a focus on Japan have been published. To clarify the effect of time on PRRSV genomic evolution, we sequenced the open reading frame 5 (600 or 603 bases) obtained from Japanese PRRSV isolates for three periods (1992-1993, 2000-2001, and 2007-2008) and compared their phylogenetic relationships. Assessment of mean pairwise homology of nucleotide sequences of PRRSV isolates indicated a trend towards increasing heterogeneity over time. In addition, we newly detected a virus classified in cluster IV, indicative of the increasing genetic variation of PRRSV in Japan.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available