Journal
MICROBIOLOGY AND IMMUNOLOGY
Volume 53, Issue 6, Pages 356-359Publisher
WILEY
DOI: 10.1111/j.1348-0421.2009.00132.x
Keywords
norovirus; seroepidemiology; virus-like particles
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Funding
- Research on Food Safety from Ministry of Health, Labor, and Welfare, Japan
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The serological prevalence of IgG antibody to seven NoV strains (GI.1, GI.4, GII.3, GII.4, GII.10, GII.12 and GII.15) among inhabitants aged 1-62 years of Aichi Prefecture, Japan was studied. Age-related seroprevalence was measured by ELISA using baculovirus-expressed recombinant VLP antigens. Seropositive rates for all seven VLP antigens gradually increased with age. Among the tested antigens, the highest seropositive rate was for the GII.4 strain. This result is consistent with the recent epidemic of NoV infection due to GII.4 strain in Japan.
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