Journal
MICROBIOLOGY AND IMMUNOLOGY
Volume 52, Issue 2, Pages 128-133Publisher
WILEY
DOI: 10.1111/j.1348-0421.2008.00028.x
Keywords
Bordetella; effectors; type III secretion system; vaccine
Categories
Ask authors/readers for more resources
B. pertussis is a causative agent of whooping cough (pertussis) in humans. Despite wide-scale vaccination in many countries, there is serious concern about pertussis as a re-emerging disease. Re-emergence of pertussis may be explained by several factors: the short duration of protection by the currently available acellular pertussis vaccine, an increase in asymptomatic adult carriers and expansion of strains with certain antigenic variations which are not covered by currently available vaccines. To develop safer and more efficacious vaccines which confer more prolonged protection, researchers are focusing on identification and characterization of new virulence factors. One candidate for protective antigens is the type III secretion system and its secreted proteins.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available