4.6 Review

Evasion from NK cell-mediated immune responses by HIV-1

Journal

MICROBES AND INFECTION
Volume 14, Issue 11, Pages 904-915

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.micinf.2012.05.001

Keywords

HIV-1; NK cells; Escape; Innate immunity; Vaccine

Funding

  1. NIAID NIH HHS [R01 AI067031] Funding Source: Medline

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Human immunodeficiency virus type 1 (HIV-1) mostly owes its success to its ability to evade host immune responses. Understanding viral immune escape mechanisms is a prerequisite to improve future HIV-1 vaccine design. This review focuses on the strategies that HIV-1 has evolved to evade recognition by natural killer (NK) cells. (C) 2012 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

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