Journal
MICROBES AND INFECTION
Volume 14, Issue 3, Pages 207-216Publisher
ELSEVIER
DOI: 10.1016/j.micinf.2011.10.001
Keywords
Innate immunity; Inflammation; Hepcidin
Categories
Funding
- NIH [DK064750, ES014638]
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Host antimicrobial mechanisms reduce iron availability to pathogens. Iron proteins influencing the innate immune response include hepcidin, lactoferrin, siderocalin, haptoglobin, hemopexin, Nrampl, ferroportin and the transferrin receptor. Numerous global health threats are influenced by iron status and provide examples of our growing understanding of the connections between infection and iron metabolism. (C) 2011 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.
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