Journal
MICROBES AND INFECTION
Volume 13, Issue 14-15, Pages 1133-1145Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.micinf.2011.07.011
Keywords
Innate immunity; Pseudomonas aeruginosa; Murine models; Pneumonia
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Funding
- Burroughs
- National Institute of Allergy and Infectious Diseases [R01 AI081825]
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Innate immune responses play a critical role in controlling acute infections due to Pseudomonas aeruginosa in both mice and in humans. In this review we focus on innate immune recognition and clearance mechanisms that are important for controlling P. aeruginosa in the mammalian lung, with particular attention to those that influence the outcome of in vivo infection in murine models. (C) 2011 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.
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