Journal
MICROBES AND INFECTION
Volume 13, Issue 7, Pages 649-662Publisher
ELSEVIER
DOI: 10.1016/j.micinf.2011.03.004
Keywords
Chlamydial persistence; Aberrant body; Tissue tropism; Bacterial/viral co-infection; Sexually-transmitted infection; Chlamydiaceae
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Funding
- NIH/NIAID [AI078373-01A1, AI082322-01]
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Under stress, chlamydiae can enter a non-infectious but viable state termed persistence. In the absence of a tractable genetic system, persistence induction provides an important experimental tool with which to study these fascinating organisms. This review will discuss examples of: i) persistence studies that have illuminated critical chlamydiae/host interactions; and ii) novel persistence models that will do so in the future. (C) 2011 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.
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