4.6 Article

The contribution of animal models to the understanding of the host range and virulence of influenza A viruses

Journal

MICROBES AND INFECTION
Volume 13, Issue 5, Pages 502-515

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.micinf.2011.01.014

Keywords

Influenza A virus; Host range; Virulence; Pathogenesis; Animal models

Funding

  1. NIAID/NIH

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Since ferrets were first used in 1933 during the initial isolation of influenza A viruses, animal models have been critical for influenza research. The following review discusses the contribution of mice, ferrets, and non-human primates to the study of influenza virus host range and pathogenicity. Published by Elsevier Masson SAS on behalf of Institut Pasteur.

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