4.6 Review

Molecular mechanisms involved in the early steps of flavivirus cell entry

Journal

MICROBES AND INFECTION
Volume 13, Issue 1, Pages 1-9

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.micinf.2010.09.005

Keywords

Flavivirus; Cell entry; Receptor; Endocytosis; Envelope protein; pH environment

Funding

  1. NIH [1 R01 AI76331]
  2. NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES [R01AI076331] Funding Source: NIH RePORTER

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Flaviviruses enter their host cells by receptor-mediated endocytosis, a well-orchestrated process of receptor recognition, penetration and uncoating. Recent findings on these early steps in the life cycle of flaviviruses are the focus of this review. (C) 2010 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

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