Journal
MICROBES AND INFECTION
Volume 12, Issue 14-15, Pages 1144-1152Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.micinf.2010.08.012
Keywords
Myxoma virus; Poxvirus; Oncolytic virus; Immunoregulatory factors
Categories
Funding
- NIH [AI080607, CA13854]
- Bankhead Coley Foundation
Ask authors/readers for more resources
Myxoma virus (MYXV) is a poxvirus with a strict rabbit-specific host-tropism for pathogenesis. The immunoregulatory factors encoded by MYXV can suppress some functions of immune effectors from other species. We review their mechanisms of action, implications in therapeutics and the potential to improve MYXV as an oncolytic agent in humans. (C) 2010 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
