Journal
MICROBES AND INFECTION
Volume 12, Issue 5, Pages 337-345Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.micinf.2010.01.009
Keywords
Ehrlichia; Tandem repeat proteins; Ankyrin proteins; Effector; Host-pathogen interaction
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Funding
- National Institute of Allergy and Infectious Diseases [AI 071145, AI 069270]
- Clayton Foundation for Research
- NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES [R01AI071145, R21AI069270] Funding Source: NIH RePORTER
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Ehrlichia chaffeensis is an obligately intracellular bacterium that exhibits tropism for mononuclear phagocytes and survives by reprogramming the host cell. Here we review new information regarding the newly characterized effector molecules and the complex network of molecular host-pathogen interactions that the organism exploits enabling it to thrive and persist intracellularly. (C) 2010 Elsevier Masson SAS. All rights reserved.
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