Journal
MICROBES AND INFECTION
Volume 12, Issue 6, Pages 421-427Publisher
ELSEVIER
DOI: 10.1016/j.micinf.2010.02.002
Keywords
Natural selection; Population genetics; Host-pathogen interactions
Categories
Funding
- Istituto Superiore di Sanita'
- EMPRO
- AVIP EC [WP6]
- nGIN EC [WP7]
- Japan Health Science Foundation
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The hygiene hypothesis relies on the assumption that humans have adapted to a pathogen-rich environment that no longer exists in industrialized societies. Recent advances in molecular immunology and population genetics allow deeper insight into the evolution and co-evolution of host pathogen interactions and, therefore, into the foundations of the hygiene hypothesis. (C) 2010 Elsevier Masson SAS. All rights reserved.
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