4.6 Review

Impact of aging on viral infections

Journal

MICROBES AND INFECTION
Volume 12, Issue 14-15, Pages 1120-1124

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.micinf.2010.08.009

Keywords

Aging; Viral infection; Immunity

Funding

  1. National Institute on Aging [AG028082, AG033049]
  2. American Heart Association [0940006N]

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Older people are more susceptible to a variety of viral infections, including those that induce respiratory disease, resulting in higher morbidity and mortality than younger people. Aging impacts both innate and adaptive arms of the immune system to impair control of viral infections. This review will summarize key findings on how aging impacts immunity to viral infection. (C) 2010 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

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