Journal
MICROBES AND INFECTION
Volume 11, Issue 5, Pages 584-588Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.micinf.2009.04.001
Keywords
Helper T cells; Cytokines; Inflammation; Autoimmunity
Categories
Funding
- National Institutes of Health
- MID Anderson Cancer Center
- Cancer Research Institute
- American Lung Association and Lymphoma and Leukemia Society
Ask authors/readers for more resources
After activation, CD4+ helper T (Th) cells differentiate into cytokine-secreting effector subsets. A novel subset of CD4+ helper T (Th) cells that produce two related cytokines IL-17 and IL-17F has been recently identified and shown to play critical function in inflammation and autoimmunity. Here I summarize recent work by us as well as other investigators in understanding the transcriptional regulation of Th17-cell differentiation, their developmental relationship with regulatory T cells and the function of IL-17 and IL-17F in vivo. (C) 2009 Elsevier Masson SAS. All fights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
