Journal
METALLOMICS
Volume 6, Issue 2, Pages 233-236Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3mt00265a
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Funding
- Beneficentia Stiftung (Vaduz, Liechtenstein)
- AIRC [IG-12085]
- Cost Action [CM1105]
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The reaction of Auoxo6, a dinuclear gold(III) complex, with the model protein bovine pancreatic ribonuclease is explored here by X-ray diffraction and ESI mass spectrometry. Data provide clues on the processes of adduct formation and of enzyme inhibition and, inductively, on the likely mode of action of this metallodrug.
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