Journal
MEMORIAS DO INSTITUTO OSWALDO CRUZ
Volume 103, Issue 6, Pages 598-601Publisher
FUNDACO OSWALDO CRUZ
DOI: 10.1590/S0074-02762008000600015
Keywords
calpain-like; Trypanosoma cruzi; stress; metacyclogenesis
Categories
Funding
- CNPq
- PRONEX (Fundacao Araucaria)
- PAPES-FIOCRUZ
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Calpains are calcium-dependent cysteine proteinases found in all living organisms and are involved in diverse cellular processes. Calpain-like proteins have been reported after in silico analysis of the Tritryps genome and are believed to play important roles in cell functions of trypanosomatids. We describe the characterization of a member of this family, which is differentially expressed during the life-cycle of Trypanosoma cruzi.
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