Journal
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
Volume 44, Issue 9, Pages 1653-1662Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1249/MSS.0b013e31825871fa
Keywords
ESTROGENS; MUSCLE; METABOLISM; CARDIAC; SEX; EXERCISE
Categories
Funding
- NIH [AG031575, HL50560, AG031743, AG036827]
- National Center for Research Resources, a component of NIH [P20 RR016475]
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SPANGENBURG, E. E., P. C. GEIGER, L. A. LEINWAND, and D. A. LOWE. Regulation of Physiological and Metabolic Function of Muscle by Female Sex Steroids. Med. Sci. Sports Exerc., Vol. 44, No. 9, pp. 1653-1662, 2012. The ability of female sex steroids to regulate tissue function has long been appreciated; however, their role in the regulation of striated muscle function has received considerably less attention. The purpose of this symposium review was to document recent evidence indicating the role female sex steroids have in defining the functional characteristics of striated muscle. The presentations provide substantial evidence indicating that estrogens are critical to the physiological and metabolic regulations of striated muscle; thus, when considering women's health issues, striated muscle must included as an important target tissue along with other classically thought of estrogen-sensitive tissues.
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