Synthetic β-(1→3)-D-glucooligosaccharides: model compounds for the mechanistic study of β-(1→3)-D-glucan bioactivities and design of antifungal vaccines

Synthetic methods used for the preparation of linear beta-(1 -> 3)-d-glucooligosaccharides with three and more monosaccharide units and their conjugates with carrier proteins, as well as the application of such derivatives in the mechanistic study of bioactivites of natural beta-(1 -> 3)-d-glucans and in the design of conjugated antifungal vaccines are considered.