Journal
MEDICINAL CHEMISTRY RESEARCH
Volume 23, Issue 10, Pages 4404-4413Publisher
SPRINGER BIRKHAUSER
DOI: 10.1007/s00044-014-1006-0
Keywords
Amino bis (benzothiazole); 2-amino benzothiazole; Sharpless conditions; Antibacterial activity; Antifungal activity; Anticancer activity
Categories
Funding
- CSIR, New Delhi
- S.E.R.C., Department of Science & Technology, Government of India [SR/FT/CS-031/2010]
Ask authors/readers for more resources
A new series of fluoro 1,2,3-triazole tagged amino bis (benzothiazole) derivatives 8, 9 were prepared starting from 2-amino benzothiazole in four steps via amination, cyclization, alkylation followed by reaction with various azides under sharpless conditions through click chemistry approach. All newly synthesized compounds were screened for their antimicrobial and cytotoxic activity against four human cancer cell lines (U937, THP-1, Colo205, and A549), and promising compounds have been identified.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available