Heart Rate Recovery Is Impaired in Patients with Psoriasis

Objective: The aim of this study was to investigate the relationship between psoriasis and heart rate recovery (HRR) index. Patients and Methods: A total of 50 patients with a diagnosis of psoriasis and 32 healthy volunteers were included in the study. In all patients, a stress test was performed to calculate the HRR index in a manner which aimed to reach the age-specific maximum heart rate. HRR indices were calculated in all patients and controls. Results: HRR (beats/minute) indices after the 1st (HRR 1, 26 +/- 10 vs. 33 +/- 8, p = 0.002), 2nd (44 +/- 11 vs. 50 +/- 6, p = 0.002), 3rd (51 +/- 7 vs. 63 +/- 8, p < 0.001), 4th (54 +/- 7 vs. 65 +/- 8, p < 0.001) and 5th (57 +/- 8 vs. 70 +/- 10, p < 0.001) minutes of the recovery period were significantly lower in the psoriasis group compared to healthy controls. In addition, HRR 1 was significantly correlated with duration of psoriasis (r = 0.541, p < 0.001) and psoriasis area and severity index score (r = 0.511, p < 0.001). Conclusion: HRR was lower in patients with psoriasis. Given the prognostic value of this test, patients with psoriasis might be at risk for future cardiovascular events and cardiovascular mortality. Copyright (C) 2013 S. Karger AG, Basel