Journal
MEDICAL PHYSICS
Volume 42, Issue 1, Pages 165-169Publisher
WILEY
DOI: 10.1118/1.4903265
Keywords
BNCT; prompt gamma ray; GPU; SPECT
Funding
- Leading Foreign Research Institute Recruitment Program through National Research Foundation of Korea (NRF) - Ministry of Science, Information and Communication Technologies (ICT) [2009-00420]
- Leading Foreign Research Institute Recruitment Program through National Research Foundation of Korea (NRF) - Ministry of Science, Future Planning (MSIP) [2009-00420]
- Radiation Technology Research and Development program, Republic of Korea [2013043498]
- National Research Foundation of Korea [2009-00420] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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Purpose: The purpose of this research is to perform the fast reconstruction of a prompt gamma ray image using a graphics processing unit (GPU) computation from boron neutron capture therapy (BNCT) simulations. Methods: To evaluate the accuracy of the reconstructed image, a phantom including four boron uptake regions (BURs) was used in the simulation. After the Monte Carlo simulation of the BNCT, the modified ordered subset expectation maximization reconstruction algorithm using the GPU computation was used to reconstruct the images with fewer projections. The computation times for image reconstruction were compared between the GPU and the central processing unit (CPU). Also, the accuracy of the reconstructed image was evaluated by a receiver operating characteristic (ROC) curve analysis. Results: The image reconstruction time using the GPU was 196 times faster than the conventional reconstruction time using the CPU. For the four BURs, the area under curve values from the ROC curve were 0.6726 (A-region), 0.6890 (B-region), 0.7384 (C-region), and 0.8009 (D-region). Conclusions: The tomographic image using the prompt gamma ray event from the BNCT simulation was acquired using the GPU computation in order to perform a fast reconstruction during treatment. The authors verified the feasibility of the prompt gamma ray image reconstruction using the GPU computation for BNCT simulations. (c) 2015 American Association of Physicists in Medicine.
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