Journal
MEDICAL MYCOLOGY
Volume 51, Issue 4, Pages 405-412Publisher
OXFORD UNIV PRESS
DOI: 10.3109/13693786.2012.719648
Keywords
Sporothrix mexicana; Sporothrix globosa; Sporothrix schenckii complex; sporotrichosis; calmodulin; first isolation; Brazil
Categories
Funding
- Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [2011/07350-1]
- Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior [BEX 2325/11-0]
- FAPESP [2009/54024-2]
- CNPq
- CAPES
Ask authors/readers for more resources
Sporothrix schenckii sensu lato is a complex of thermally dimorphic species whose natural habitats are soil and plant materials. However, the traumatic implantation of the species into human skin is traditionally thought to be the route leading to the fungal disease sporotrichosis. The complex contains Sporotrhix mexicana, S. globosa, S. brasiliensis, S. luriei, in addition to S. schenckii sensu stricto. In this study we evaluated the differences among these species relative to their frequency in the environment and in human hosts, as well as discuss their remarkable diverse pathogenicity. Today, S. brasiliensis is epidemic in and geographically restricted to Brazil. In contrast, S. mexicana and S. globosa have rarely been reported over the decades. We discovered that the species have been present in collections from clinical cases since 1955 and were able to re-identify six isolates originally classified as S. schenckii as Sporothrix mexicana (three isolates) and Sporothrix globosa (three isolates). Despite their long presence as potential human pathogens they have not shown any increase in frequency as etiologic agents of human infections.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available