4.5 Article

Evaluation of fungal-specific fluorescent labeled echinocandin probes as diagnostic adjuncts

Journal

MEDICAL MYCOLOGY
Volume 51, Issue 1, Pages 103-107

Publisher

OXFORD UNIV PRESS
DOI: 10.3109/13693786.2012.685767

Keywords

diagnostics; invasive fungal infections; fluorescence labeled anti-fungal; caspofungin

Funding

  1. NIH [AI069397, GM30717]
  2. Merck

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The diagnosis of invasive fungal infections from radiographic imaging is non-specific and problematic. As a first step toward increasing specificity, we describe the development of a broad-spectrum fungal-specific targeting molecule, which when modified with a fluorescent label fully retains its targeting properties, and provides a basis for future imaging applications.

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