Journal
MEDICAL MYCOLOGY
Volume 50, Issue 3, Pages 276-280Publisher
OXFORD UNIV PRESS
DOI: 10.3109/13693786.2011.604862
Keywords
prevalence; yeast species; Candida; HIV; oropharyngeal candidiasis
Categories
Funding
- Board of the Dublin Dental University Hospital
- Company of Biologists Ltd, UK
- AIDS Support Organization TASO management
Ask authors/readers for more resources
Oropharyngeal candidiasis remains a significant clinical problem in HIV-infected and AIDS patients in regions of Africa where anti-retroviral therapy isn't readily available. In this study we identified the yeast populations associated with oral lesions in HIV-infected patients in Southwest Uganda who were receiving treatment with nystatin and topical clotrimazole. Samples were taken from 605 patients and 316 (52%) of these yielded yeast growth following incubation on Sabouraud dextrose agar. Samples were subsequently re-plated on CHROMagar Candida medium to facilitate identification of the yeast species present. The majority (56%) of culture-positive samples yielded a mix of two or more species. Candida albicans was present in 87% (274/316) of patient samples and accounted for 87% (120/138) of single species samples. Candida glabrata, Candida tropicalis and Candida norvegensis were also found in cultures that yielded a single species. No Candida dubliniensis isolates were identified in this population.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available