4.5 Article

Paracoccidioidomycosis: an unusual presentation in a young girl disclosing an unnoted HIV-infection

Journal

MEDICAL MYCOLOGY
Volume 48, Issue 1, Pages 182-187

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.3109/13693780902893405

Keywords

paracoccidioidomycosis; AIDS; co-infection; opportunistic fungal infection; cutaneous lesions

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The association of paracoccidioidomycosis with AIDS is apparently less frequent than expected. The authors present an unusual case of paracoccidioidomycosis in a 13-year-old female student which was later found to be the first opportunistic infection in the course of the patient's HIV-infection. The clinical presentation followed an accidental incised wound on the palmar region initially described as a 'sporotrichotic-chancre'. After good response under sulfamethoxazole-trimethoprin, the patient relapsed and presented an associated oral candidiasis. HIV-infection was documented and additional investigation showed CD4(+) T-cells=22/mm(3), CD8(+)=280 cell/mm(3) and viral load=4,043 log. This case report presents an uncommon dermatological-clinical picture in the youngest patient in which such association has been reported to date.

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