Journal
MEDICAL MYCOLOGY
Volume 47, Issue -, Pages S42-S46Publisher
OXFORD UNIV PRESS
DOI: 10.1080/13693780802562092
Keywords
Aspergillus terreus; accessory conidia; cryptic species
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Aspergillus terreus can cause invasive infections in humans, which are often refractory to therapy with the antifungal drug amphotericin B and have a propensity to dissemination. The organism has diverse colony morphology, and sub-typing studies have demonstrated that isolates of A. terreus are diverse in their genotypes. However, detailed phylogenetic studies of section Terrei employing sequence information from protein coding regions have not been thus far attempted. Interestingly, A. terreus produces unicellular forms called accessory conidia in vitro and during infection; the clinical relevance of these structures are not well understood. This paper presents an overview of the morphology, species identification strategies, and molecular epidemiology of A. terreus.
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