Related references
Note: Only part of the references are listed.Aspirin inhibits lipopolysaccharide-induced COX-2 expression and PGE2 production in porcine alveolar macrophages by modulating protein kinase C and protein tyrosine phosphatase activity
Yuzhong Duan et al.
BMB REPORTS (2014)
Anti-inflammatory activities and mechanisms of Artemisia asiatica ethanol extract
Deok Jeong et al.
JOURNAL OF ETHNOPHARMACOLOGY (2014)
Myrsine seguinii ethanolic extract and its active component quercetin inhibit macrophage activation and peritonitis induced by LPS by targeting to Syk/Src/IRAK-1
Woo Seok Yang et al.
JOURNAL OF ETHNOPHARMACOLOGY (2014)
Syk and Src are major pharmacological targets of a Cerbera manghas methanol extract with kaempferol-based anti-inflammatory activity
Hye Yoon Jeong et al.
JOURNAL OF ETHNOPHARMACOLOGY (2014)
Inflammatory and microenvironmental factors involved in breast cancer progression
Mina Ham et al.
ARCHIVES OF PHARMACAL RESEARCH (2013)
Adipose tissue macrophages in the development of obesity-induced inflammation, insulin resistance and type 2 Diabetes
Jongsoon Lee
ARCHIVES OF PHARMACAL RESEARCH (2013)
Aromadendrin Inhibits Lipopolysaccharide-Induced Nuclear Trans location of NF-κB and Phosphorylation of JNK in RAW 264.7 Macrophage Cells
Jae-Won Lee et al.
BIOMOLECULES & THERAPEUTICS (2013)
Polyamines and Their Metabolites as Diagnostic Markers of Human Diseases
Myung Hee Park et al.
BIOMOLECULES & THERAPEUTICS (2013)
Mycobacterium tuberculosis-induced expression of granulocyte-macrophage colony stimulating factor is mediated by PI3-K/MEK1/p38 MAPK signaling pathway
Jang-Eun Cho et al.
BMB REPORTS (2013)
Emerging role of sirtuins on tumorigenesis: possible link between aging and cancer
Yong I. Cha et al.
BMB REPORTS (2013)
Inhibitors of switch kinase 'spleen tyrosine kinase' in inflammation and immune-mediated disorders: A review
Maninder Kaur et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2013)
Quercetin disrupts tyrosine-phosphorylated phosphatidylinositol 3-kinase and myeloid differentiation factor-88 association, and inhibits MAPK/AP-1 and IKK/NF-κB-induced inflammatory mediators production in RAW 264.7 cells
Mehari Endale et al.
IMMUNOBIOLOGY (2013)
Methanol extract of Hopea odorata suppresses inflammatory responses via the direct inhibition of multiple kinases
Yanyan Yang et al.
JOURNAL OF ETHNOPHARMACOLOGY (2013)
Methanol extract of Evodia lepta displays Syk/Src-targeted anti-inflammatory activity
Ju Young Yoon et al.
JOURNAL OF ETHNOPHARMACOLOGY (2013)
In vitro and in vivo anti-inflammatory effect of Rhodomyrtus tomentosa methanol extract
Deok Jeong et al.
JOURNAL OF ETHNOPHARMACOLOGY (2013)
IRAK1/4-Targeted Anti-Inflammatory Action of Caffeic Acid
Woo Seok Yang et al.
MEDIATORS OF INFLAMMATION (2013)
The Soluble Form of the Cellular Prion Protein Enhances Phagocytic Activity and Cytokine Production by Human Monocytes Via Activation of ERK and NF-κB
Jae-Won Jeon et al.
Immune Network (2013)
Regulation of Intestinal Homeostasis by Innate Immune Cells
Hisako Kayama et al.
Immune Network (2013)
Inhibition of Syk activity by R788 in platelets prevents remote lung tissue damage after mesenteric ischemia-reperfusion injury
Peter H. Lapchak et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2012)
The SYK side of TLR4: signalling mechanisms in response to LPS and minimally oxidized LDL
Yury I. Miller et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Syk-dependent signaling pathways in neutrophils and macrophages are indispensable in the pathogenesis of anti-collagen antibody-induced arthritis
Naoko Ozaki et al.
INTERNATIONAL IMMUNOLOGY (2012)
Src/NF-κB-targeted inhibition of LPS-induced macrophage activation and dextran sodium sulphate-induced colitis by Archidendron clypearia methanol extract
Woo Seok Yang et al.
JOURNAL OF ETHNOPHARMACOLOGY (2012)
The ability of an ethanol extract of Cinnamomum cassia to inhibit Src and spleen tyrosine kinase activity contributes to its anti-inflammatory action
Tao Yu et al.
JOURNAL OF ETHNOPHARMACOLOGY (2012)
The Pivotal Role of TBK1 in Inflammatory Responses Mediated by Macrophages
Tao Yu et al.
MEDIATORS OF INFLAMMATION (2012)
The Role of Src Kinase inMacrophage-Mediated Inflammatory Responses
Se Eun Byeon et al.
MEDIATORS OF INFLAMMATION (2012)
Specific Inhibition of Spleen Tyrosine Kinase Suppresses Leukocyte Immune Function and Inflammation in Animal Models of Rheumatoid Arthritis
Greg Coffey et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2012)
Complex phosphorylation dynamics control the composition of the Syk interactome in B cells
Hanibal Bohnenberger et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2011)
Proteomic Studies of Syk-Interacting Proteins Using a Novel Amine-Specific Isotope Tag and GFP Nanotrap
Jacob A. Galan et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2011)
Spleen tyrosine kinase inhibition prevents tissue damage after ischemia-reperfusion
Omer Nuri Pamuk et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2010)
Suppression of Skin and Kidney Disease by Inhibition of Spleen Tyrosine Kinase in Lupus-Prone Mice
Guo-Min Deng et al.
ARTHRITIS AND RHEUMATISM (2010)
A Spleen Tyrosine Kinase Inhibitor Reduces the Severity of Established Glomerulonephritis
Jennifer Smith et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2010)
Anti-inflammatory actions of Syk inhibitors in macrophages involve non-specific inhibition of toll-like receptors-mediated JNK signaling pathway
Ying-Cing Lin et al.
MOLECULAR IMMUNOLOGY (2010)
ZAP-70: An Essential Kinase in T-cell Signaling
Haopeng Wang et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2010)
The SYK tyrosine kinase: a crucial player in diverse biological functions
Attila Mocsai et al.
NATURE REVIEWS IMMUNOLOGY (2010)
Of mice and men: an open-label pilot study for treatment of immune thrombocytopenic purpura by an inhibitor of Syk
Anna Podolanczuk et al.
BLOOD (2009)
Neutrophil-specific deletion of Syk kinase results in reduced host defense to bacterial infection
Jessica A. Van Ziffle et al.
BLOOD (2009)
Lipoprotein Accumulation in Macrophages via Toll-Like Receptor-4-Dependent Fluid Phase Uptake
Soo-Ho Choi et al.
CIRCULATION RESEARCH (2009)
Macrophages Generate Reactive Oxygen Species in Response to Minimally Oxidized Low-Density Lipoprotein Toll-Like Receptor 4-and Spleen Tyrosine Kinase-Dependent Activation of NADPH Oxidase 2
Yun Soo Bae et al.
CIRCULATION RESEARCH (2009)
Therapeutic prospect of Syk inhibitors
Paolo Ruzza et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2009)
Autoinhibition and adapter function of Syk
Yogesh Kulathu et al.
IMMUNOLOGICAL REVIEWS (2009)
The structure, regulation, and function of ZAP-70
Byron B. Au-Yeung et al.
IMMUNOLOGICAL REVIEWS (2009)
Distinct role of spleen tyrosine kinase in the early phosphorylation of inhibitor of κBα via activation of the phosphoinositide-3-kinase and Akt pathways
Yong Gyu Lee et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2009)
Ability of certain plant extracts traditionally used to treat ciguatera fish poisoning to inhibit nitric oxide production in RAW 264.7 macrophages
Shilpa Kumar-Roine et al.
JOURNAL OF ETHNOPHARMACOLOGY (2009)
RhoH Plays Critical Roles in FcεRI-Dependent Signal Transduction in Mast Cells
Hiroyo Oda et al.
JOURNAL OF IMMUNOLOGY (2009)
Folate-Targeted Hapten Immunotherapy of Adjuvant-induced Arthritis: Comparison of Hapten Potencies
Young-Su Yi et al.
MOLECULAR PHARMACEUTICS (2009)
Identification of a dendritic cell receptor that couples sensing of necrosis to immunity
David Sancho et al.
NATURE (2009)
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence
Olaf Gross et al.
NATURE (2009)
Signalling through C-type lectin receptors: shaping immune responses
Teunis B. H. Geijtenbeek et al.
NATURE REVIEWS IMMUNOLOGY (2009)
Treatment of Rheumatoid Arthritis With a Syk Kinase Inhibitor A Twelve-Week, Randomized, Placebo-Controlled Trial
Michael E. Weinblatt et al.
ARTHRITIS AND RHEUMATISM (2008)
An orally bioavailable spleen tyrosine kinase inhibitor delays disease progression and prolongs survival in murine lupus
Frances Rena Bahjat et al.
ARTHRITIS AND RHEUMATISM (2008)
Spleen tyrosine kinase: a novel target for therapeutic intervention of rheumatoid arthritis
Malini Bajpai et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2008)
CLEC9A is a novel activation C-type lectin-like receptor expressed on BDCA3+ dendritic cells and a subset of monocytes
Cristal Huysamen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Draper-dependent glial phagocytic activity is mediated by Src and Syk family kinase signalling
Jennifer S. Ziegenfuss et al.
NATURE (2008)
CLEC5A is critical for dengue-virus-induced lethal disease
Szu-Ting Chen et al.
NATURE (2008)
Mincle is an ITAM-coupled activating receptor that senses damaged cells
Sho Yamasaki et al.
NATURE IMMUNOLOGY (2008)
Mechanisms of disease: Systemic lupus erythematosus
Anisur Rahman et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Syk inhibitors as treatment for allergic rhinitis
Esteban S. Masuda et al.
PULMONARY PHARMACOLOGY & THERAPEUTICS (2008)
Spleen tyrosine kinase Syk is critical for sustained leukocyte adhesion during inflammation in vivo
David Frommhold et al.
BMC IMMUNOLOGY (2007)
Immunoreceptor-like signaling by β2 and β3 integrins
Zoltan Jakus et al.
TRENDS IN CELL BIOLOGY (2007)
Inflammation and bone erosion are suppressed in models of rheumatoid arthritis following treatment with a novel Syk inhibitor
Polly R. Pine et al.
CLINICAL IMMUNOLOGY (2007)
Tyrosine kinase Syk associates with toll-like receptor 4 and regulates signaling in human monocytic cells
Anu Chaudhary et al.
IMMUNOLOGY AND CELL BIOLOGY (2007)
Chronic inflammation:: importance of NOD2 and NALP3 in interleukin-1β generation
L. Ferrero-Miliani et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2007)
Spleen tyrosine kinase (Syk), a novel target of curcumin, is required for B lymphoma growth
Murali Gururajan et al.
JOURNAL OF IMMUNOLOGY (2007)
Spleen tyrosine kinase syk is necessary for E-Selectin-induced alpha(L)beta 2 integrin-mediated rolling on intercellular adhesion molecule-1
Alexander Zarbock et al.
IMMUNITY (2007)
Integrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifs
Attila Mocsai et al.
NATURE IMMUNOLOGY (2006)
Identification of the Syk kinase inhibitor R112 by a human mast cell screen
Alexander B. Rossi et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2006)
Artemisolide from Artemisia asiatica:: Nuclear factor-κB (NF-κB) inhibitor suppressing prostaglandin E2 and nitric oxide production in macrophages
Alavalla Matta Reddy et al.
ARCHIVES OF PHARMACAL RESEARCH (2006)
Dectin-1 activates Syk tyrosine kinase in a dynamic subset of macrophages for reactive oxygen production
DM Underhill et al.
BLOOD (2005)
Targeting kinases in asthma
K Blease
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2005)
Synthetic studies on novel Syk inhibitors. Part 1: Synthesis and structure-activity relationships of pyrimidine-5-carboxamide derivatives
H Hisamichi et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2005)
Enhanced Toll-like receptor responses in the absence of signaling adaptor DAP12
JA Hamerman et al.
NATURE IMMUNOLOGY (2005)
Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins
NC Rogers et al.
IMMUNITY (2005)
An intranasal Syk-kinase inhibitor (R112) improves the symptoms of seasonal allergic rhinitis in a park environment
EO Meltzer et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2005)
A molecular understanding of mast cell activation and the promise of anti-allergic therapeutics
M Kovarova et al.
CURRENT MEDICINAL CHEMISTRY (2004)
Targeting Syk as a treatment for allergic and and autoimmune disorders
BR Wong et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2004)
NFAM1, an immunoreceptor tyrosine-based activation motif-bearing molecule that regulates B cell development and signaling
M Ohtsuka et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
The orally available spleen tyrosine kinase inhibitor 2-[7-(3,4-dimethoxyphenyl)-imidazo[1,2-c]pyrimidin-5-ylamino]-nicotinamide dihydrochloride (BAY 61-3606) blocks antigen-induced airway inflammation in rodents
N Yamamoto et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)
Cbl-b negatively regulates B cell antigen receptor signaling in mature B cells through ubiquitination of the tyrosine kinase Syk
HW Sohn et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Piceatannol inhibits TNF-induced NF-κB activation and NF-κB-mediated gene expression through suppression of IκBα kinase and p65 phosphorylation
K Ashikawa et al.
JOURNAL OF IMMUNOLOGY (2002)
The N-terminal SH2 domains of Syk and ZAP-70 mediate phosphotyrosine-independent binding to integrin β cytoplasmic domains
DG Woodside et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
ITAM-based interaction of ERM proteins with Syk mediates signaling by the leukocyte adhesion receptor PSGL-1
A Urzainqui et al.
IMMUNITY (2002)
Regulation of signaling in B cells through the phosphorylation of Syk on linker region tyrosines - A mechanism for negative signaling by the Lyn tyrosine kinase
JJ Hong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Natural cytotoxicity uncoupled from the Syk and ZAP-70 intracellular kinases
F Colucci et al.
NATURE IMMUNOLOGY (2002)
Phagocytic signaling strategies:: Fcγ receptor-mediated phagocytosis as a model system
D Cox et al.
SEMINARS IN IMMUNOLOGY (2001)
Syk expression and novel function in a wide variety of tissues
S Yanagi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Inhibition of β2 integrin receptor and Syk kinase signaling in monocytes by the Src family kinase Fgr
CM Vines et al.
IMMUNITY (2001)
Visualization of Syk-antigen receptor interactions using green fluorescent protein: Differential roles for Syk and Lyn in the regulation of receptor capping and internalization
H Ma et al.
JOURNAL OF IMMUNOLOGY (2001)
BCAP: The tyrosine kinase substrate that connects B cell receptor to phosphoinositide 3-kinase activation
T Okada et al.
IMMUNITY (2000)
Regulation of protein kinase CβI by two protein-tyrosine kinases, Btk and Syk
Y Kawakami et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
LAT is essential for FcεRI-mediated mast cell activation
S Saitoh et al.
IMMUNITY (2000)
The Src homology 2 domain of Vav is required for its compartmentation to the plasma membrane and activation of C-jun NH2-terminal kinase 1
R Arudchandran et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
Tyrosine kinase SYK: essential functions for immunoreceptor signalling
M Turner et al.
IMMUNOLOGY TODAY (2000)
Share Paper
