Journal
MEDIATORS OF INFLAMMATION
Volume 2009, Issue -, Pages -Publisher
HINDAWI LTD
DOI: 10.1155/2009/132464
Keywords
-
Categories
Ask authors/readers for more resources
The aim of this study was to investigate the role of circulating growth hormone (GH), insulin growth factor-1 (IGF-1), IGF binding protein-3 (IGFBP-3), and nitric oxide (NO) concentrations in the patients suffering from Parkinson's disease (PD). The study groups were consisted of 25 patients with PD and 25 matched healthy subjects as a control. The NO level of patients in PD group (2.3 +/- 0.4 mu mol/L) was significantly lower than that in the control group (2.8 +/- 0.6 mu mol/L) (P:. 011). Although there were no statistically significant differences in the GH, IGF-1, and IGF BP-3 levels among the two groups, in this preliminary study, we found low NO and mildly elevated IGF-1 levels in the patients with PD. The results may be associated with adaptation or protective mechanisms in the neurodegenerative disease processes such as seen in the PD. Further studies should be carried out to confirm our results. Copyright (C) 2009 Deniz Tuncel et al.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available