Journal
REVISTA DO INSTITUTO DE MEDICINA TROPICAL DE SAO PAULO
Volume 57, Issue 2, Pages 165-167Publisher
INST MEDICINA TROPICAL SAO PAULO
DOI: 10.1590/S0036-46652015000200011
Keywords
Silver nanoparticles; Antifungal activity; Candida spp.
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Funding
- CNPq (Brazilian agency) [Process 473417/2007]
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Silver nanoparticles (AgNPs) are metal structures at the nanoscale. AgNPs have exhibited antimicrobial activities against fungi and bacteria; however synthesis of AgNPs can generate toxic waste during the reaction process. Accordingly, new routes using nontoxic compounds have been researched. The proposal of the present study was to synthesize AgNPs using ribose as a reducing agent and sodium dodecyl sulfate (SDS) as a stabilizer. The antifungal activity of these particles against C. albicans and C. tropicalis was also evaluated. Stable nanoparticles 12.5 +/- 4.9 nm (mean +/- SD) in size were obtained, which showed high activity against Candida spp. and could represent an alternative for fungal infection treatment.
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