Journal
MATURITAS
Volume 68, Issue 3, Pages 245-250Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.maturitas.2010.12.002
Keywords
Olive oil; Coronary heart disease; Case-control; Nutritional epidemiology; Food frequency questionnaire; Monounsaturated fat
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Funding
- Spanish Ministry of Health
- Navarra Regional Government
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Ischemic heart disease is the leading cause of mortality worldwide. Many mechanistic reasons support that a high consumption of olive oil may provide a protection against myocardial infarction, the hallmark of ischemic heart disease. International comparisons are also consistent with this hypothesis. Surprisingly, there is not much evidence coming from analytical epidemiological studies about this issue. A case-control study conducted at the University of Navarra (Spain) found a strong inverse association between olive oil consumption and the risk of a first non-fatal myocardial infarction. Subsequently a large cohort in Italy and another case-control study conducted in Greece also found inverse associations. However, no complete consistency exists and further prospective studies and trials are being implemented in order to obtain more complete evidence. (C) 2010 Elsevier Ireland Ltd. All rights reserved.
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