Journal
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
Volume 43, Issue -, Pages 502-505Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.msec.2014.07.052
Keywords
Functional gradient porous scaffold; Multi-scale structure; Function-based method; Additive manufacturing
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Funding
- China Post-doctoral Foundation [2012M520572]
- Tianjin Municipal Education Commission [20120401]
- Tianjin Municipal Science and Technology Commission Key [14JCZDJC39500]
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Function-based modeling is a highly flexible porous scaffold design approach for use in tissue engineering. It was recently proposed as a valid tool for constructing cellular structures by providing a compact representation of complex structures. However, current approaches have some limitations with regard to combining multiple function-based substructures. In this short communication, we propose an effective method for combination operations of multiple substructures based on given substructures and boundaries. With this proposed method, a functional gradient porous scaffold (FGPS) with multi-scale substructures could be easily constructed and directly fabricated by using additive manufacturing techniques. (C) 2014 Elsevier B.V. All rights reserved.
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