4.3 Article

Finite element analyses for optimization design of biodegradable magnesium alloy stent

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.msec.2014.05.078

Keywords

Biodegradable magnesium alloy stents (MAS); Finite element analysis; Stent design; Annealing

Funding

  1. National Basic Research Program of China (973 Program) [2012CB619101]
  2. National Science & Technology Pillar Supporting Program of China [2012BAI18B01]
  3. Foundation of Jiangsu Collaborative Innovation Center of Biomedical Functional Materials
  4. Hebei Province Science and Technology Department [12966116D]

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Stents made of biodegradable magnesium alloys are expected to provide a temporary opening into a narrowed arterial vessel until it remodels and will progressively disappear thereafter. Inferior mechanical properties and fast corrosion of the magnesium alloys are the two crucial factors that impede the clinical application of the magnesium alloy stents (MAS). In the present study, gradual strut width, addition of the peak-to-valley unit and introduction of the annealing technology were designed and investigated by finite element analysis in order to improve the performance of the MAS. Two experiments were carried out for a preliminary validation of the simulation. (C) 2014 Elsevier B.V. All rights reserved.

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