Journal
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
Volume 37, Issue -, Pages 264-270Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.msec.2014.01.023
Keywords
Electrochemical sensor; Carbon paste electrodes; Voltammetry; Haloperidol; Multi-walled carbon nanotubes; Magnetic multi-walled carbon nanotubes
Categories
Funding
- Researches and Technology Council, Baqiyatallah University of Medical Sciences, Tehran
Ask authors/readers for more resources
Multi-walled carbon nanotubes decorated with Fe3O4 nanoparticles were prepared to construct a novel sensor for the determination of haloperidol (Hp) by voltammetric methods. The morphology and properties of electrode surface were characterized by scanning electron microscopy (SEM) and electrochemical impedance spectroscopy. This modified sensor was used as a selective electrochemical sensor for the determination of trace amounts of Hp. The peak currents of differential pulse and square wave voltammograms of Hp increased linearly with its concentration in the ranges of 1.2 x 10(-3)-0.52 and 6.5 x 10(-4)-0.52 mu mol L-1, respectively. The detection limits for Hp were 7.02 x 10(-4) and 1.33 x10(-4) mu mol L-1 for differential pulse and square wave voltammetric methods, respectively. The results show that the combination of multi-walled carbon nanotubes and Fe3O4 nanoparticles causes a dramatic enhancement in the sensitivity of Hp quantification. This sensor was successfully applied to determine Hp in pharmaceutical samples and biological fluids. The fabricated electrode showed excellent reproducibility, repeatability and stability. (C) 2014 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available