Journal
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
Volume 30, Issue 4, Pages 503-508Publisher
ELSEVIER
DOI: 10.1016/j.msec.2009.01.026
Keywords
Chitosan films; Zinc oxide; Pechini method; Tween 80; Antibacterial activity; Staphylococcus aureus
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Funding
- National Science and Technology Development Council (CNPq)
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In this study ZnO nanoparticles were prepared by the Pechini method from a polyester by reacting citric acid with ethylene glycol in which the metal ions are dissolved, and incorporated into blend films of chitosan (CS) and poly (vinyl alcohol) (PVA) with different concentrations of polyoxyethylene sorbitan monooleate, Tween 80 (T80). These films were characterized by infrared spectroscopy (FTIR), X-ray diffraction (XRD), thermogravimetric analysis (TGA), scanning electron microscopy (SEM), swelling degree, degradation of films in Hank's solution and the mechanical properties. Besides these characterizations, the antibacterial activity of the films was tested, and the films containing ZnO nanoparticles showed antibacterial activity toward the bacterial species Staphylococcus aureus. The observed antibacterial activity in the composite films prepared in this work suggests that they may be used as hydrophilic wound and burn dressings. (C) 2009 Elsevier B.V. All rights reserved.
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