Enhanced oxidation of diclofenac sodium at a nano-structured electrochemical sensing film constructed by multi-wall carbon nanotubes-surfactant composite

A multi-walled carbon nanotubes (MWNTs)-dihexadecyl hydrogen phosphate (DHP) film-coated glassy carbon electrode (GCE) was fabricated, and the voltammetric determination method of diclofenac sodium was investigated on this modified electrode by using different kinds of electrochemical techniques. The results showed that this nano-structured film electrode exhibits excellent enhancement effects on the electrochemical oxidation of diclofenac sodium. The oxidation peak current of diclofenac sodium at this film-modified electrode increased significantly compared with that at a bare glassy carbon electrode. Based on the experiment outcomes a possible mechanism was proposed and discussed. The proposed method was demonstrated by using diclofenac sodium tablets and the result was satisfying. (C) 2006 Elsevier B.V. All rights reserved.