Journal
MATERIALS LETTERS
Volume 233, Issue -, Pages 78-81Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.matlet.2018.08.108
Keywords
Aligned scaffold; Graphene oxide; Chitosan; Composite materials; Shape memory materials; Bone tissue engineering
Funding
- National Natural Science Foundation of China [51273015]
- Key Laboratory of Processing and Quality Evaluation Technology of Green Plastics of China National Light Industry Council [PQETGP2018007]
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Chitosan/graphene oxide composites (CGs) were developed using directional freezing to create aligned porous three-dimensional (3D) scaffolds resembling bone lamellae. The contact provided by the anisotropic scaffolds played a critical role in guiding the alignment of MC3T3-E1 cells along the longitudinal direction. The higher mechanical strength, shape-memory, cell alignment guiding capabilities, and protein adsorption ability, render these composites potentially useful as scaffold materials in bone tissue engineering. (C) 2018 Published by Elsevier B.V.
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