Journal
MATERIALS LETTERS
Volume 234, Issue -, Pages 323-326Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.matlet.2018.09.140
Keywords
Biomaterials; Magnesium alloys; Functional; Corrosion; Anticoagulant properties; Antibacterial properties
Funding
- National Natural Science Foundation of China [31700834]
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Impressive progress has been made on the development of magnesium alloys (Mg) implants in cardiovascular and orthopedic applications due to their good mechanical strength and biodegradable. In this paper, heparin and carboxymethyl chitosan were immobilized on alkali-treated Mg to improve the hemocompatibility and antibacterial activities. Electrochemical tests revealed that the surface modified Mg obviously improved the corrosion resistance. Additionally, the surface-functionalized Mg exhibited excellent antithrombotic and antibacterial activities. (C) 2018 Elsevier B.V. All rights reserved.
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