Journal
MATERIALS LETTERS
Volume 62, Issue 29, Pages 4425-4427Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.matlet.2008.07.051
Keywords
Micelles; Thermo-responsive; Microstructure; Magnetic materials
Funding
- Program for New Century Excellent Talents in University [NCET-05-0389]
- Program of Shanghai Subject Chief Scientist [07XD14029]
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Novel magnetic micelles with the flowerlike morphology were prepared with Fe3O4 nanoparticles and poly (N-isopropylacrylamide)-block-polylactide (PNIPAAm-b-PLA) copolymers by a dialysis method. The diameter of flowerlike micelles was about 1 mu m. The core and shell of the micelles were hydrophilic, while the other area of the micelles was hydrophobic. The lower critical solution temperature (LCST) of PNIPAAm-b-PLA was about 38 degrees C. The magnetic intensity of Fe3O4 nanoparticles decreased after they were encapsulated into PNIPAAm-b-PLA micelles. Thermo-responsive and magnetic properties of the micelles would provide useful applications in the target drug delivery and release system. (C) 2008 Elsevier B.V. All rights reserved.
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