In vitro biological performance of minerals substituted hydroxyapatite coating by pulsed electrodeposition method

The present study deals with the optimization of minerals (Sr, Mg and Zn) substituted hydroxyapatite coatings (M-HAP) at different pulse on and off time (1 s, 2 s, 3 s and 4 s) by pulsed electrodeposition method. The formation of M-HAP coating was investigated using Fourier transform infrared spectroscopy (FT-IR) and X-ray diffraction studies (XRD). The morphological features and the content of Sr, Mg and Zn ions in M-HAP coated Ti-6Al-4V were investigated by high resolution scanning electron microscopy (HRSEM) and energy dispersive X-ray analysis (EDAX). The electrochemical studies were performed for M-HAP coated Ti-6Al-4V in simulated body fluid which exhibited better corrosion resistance at the prolonged pulse off time. The in vitro cell adhesion test revealed that the M-HAP coating is found appropriate for the formation of new cell growth which proves the enhanced biocompatible nature of the coating. Thus the M-HAP coating will serve as a potential candidate in orthopedic applications. (C) 2013 Elsevier B.V. All rights reserved.