Journal
RESEARCH IN MICROBIOLOGY
Volume 166, Issue 4, Pages 290-302Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.resmic.2014.09.007
Keywords
Clostridium botulinum; Botulinum neurotoxins; Genomics; Serotype
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Funding
- Department of Homeland Security Science and Technology [HSHQDC-10-C-00139]
- NIAID [IAA 120.B18]
- Office of Public Health Preparedness and Emergency Response, Centers for Disease Control and Prevention
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For nearly one hundred years, researchers have attempted to categorize botulinum neurotoxin-producing clostridia and the toxins that they produce according to biochemical characterizations, serological comparisons, and genetic analyses. Throughout this period the bacteria and their toxins have defied such attempts at categorization. Below is a description of both historic and current Clostridium botulinum strain and neurotoxin information that illustrates how each new finding has significantly added to the knowledge of the botulinum neurotoxin-containing clostridia and their diversity. Published by Elsevier Masson SAS on behalf of Institut Pasteur.
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