Journal
MASS SPECTROMETRY REVIEWS
Volume 27, Issue 4, Pages 378-394Publisher
WILEY-BLACKWELL
DOI: 10.1002/mas.20168
Keywords
mass spectrometry; tandem mass spectrometry; liquid chromatography; illicit drugs residues; wastewater; surface water
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Residues of illicit drugs have been recently found in urban wastewater and surface water. Their levels reflect the amount of drugs collectively excreted by consumers and can therefore be used to estimate drug abuse. An overview of the most widely used illicit drugs and of the analytical methods used for their detection in wastewater and surface water is presented here. Solid-phase extraction and high performance liquid chromatography-tandem mass spectrometry are the techniques that have been used for these investigations. Instrumental conditions and fragmentation patterns of illicit drugs and their metabolites are described.
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