4.7 Article

New Terpenes from the Egyptian Soft Coral Sarcophyton ehrenbergi

Journal

MARINE DRUGS
Volume 12, Issue 4, Pages 1977-1986

Publisher

MDPI AG
DOI: 10.3390/md12041977

Keywords

Sarcophyton ehrenbergi; soft coral; terpenes; cembranoids; sesquiterpenes; cytotoxic activity

Funding

  1. Science and Technology Development Fund (STDF) [1102]
  2. Grants-in-Aid for Scientific Research [25350965] Funding Source: KAKEN

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Chemical investigations of the Egyptian soft coral Sarcophyton ehrenbergi have led to the isolation of compounds 1-3 as well as the previously reported marine cembranoid diterpene sarcophine (4). Structures were elucidated by comprehensive NMR and HRMS experimentation. Isolated compounds were in vitro assayed for cytotoxic activity against human hepatocarcinoma (HepG2) and breast adenocarcinoma (MCF-7) cell lines.

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