Journal
MARINE DRUGS
Volume 12, Issue 12, Pages 5817-5838Publisher
MDPI
DOI: 10.3390/md12125817
Keywords
biological activity; biosynthetic pathway; marine organism; nucleoside; synthesis
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Funding
- National Natural Science Foundation of China [31100260]
- Natural Science Foundation of Lingnan Normal University [2L1312]
- Zhanjiang City-Science and Technology Program [2013A01024]
- Foundation of Key Laboratory of Plant Resources Conservation and Sustainable Utilization
- South China Botanical Garden
- Chinese Academy of Sciences [201210ZS]
- CAS
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Nucleosides are glycosylamines that structurally form part of nucleotide molecules, the building block of DNA and RNA. Both nucleosides and nucleotides are vital components of all living cells and involved in several key biological processes. Some of these nucleosides have been obtained from a variety of marine resources. Because of the biological importance of these compounds, this review covers 68 marine originated nucleosides and their synthetic analogs published up to June 2014. The review will focus on the structures, bioactivities, synthesis and biosynthetic processes of these compounds.
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