Journal
MARINE DRUGS
Volume 12, Issue 2, Pages 1148-1156Publisher
MDPI AG
DOI: 10.3390/md12021148
Keywords
Cladiella krempfi; eunicellin-type diterpenoid; anti-inflammatory agent; elastase
Categories
Funding
- National Science Council of Taiwan [NSC 102-2113-M-110-001-MY2]
- Aim for the Top University Program from Ministry of Education of Taiwan
- National Sun Yat-sen University-Kaohsiung Medical University Joint Project (NSYSUKMU), Taiwan [02C030117]
Ask authors/readers for more resources
Three new eunicellin-type diterpenoids, krempfielins N-P (1-3), were isolated from a Taiwanese soft coral Cladiella krempfi. The structures of the new metabolites were elucidated by extensive spectroscopic analysis and by comparison with spectroscopic data of related known compounds. Compound 3 exhibited activity to inhibit superoxide anion generation. Both 1 and3, in particular 1, were shown to display significant anti-inflammatory activity by inhibiting the elastase release in FMLP/CB-induced human neutrophils.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
