Journal
MARINE DRUGS
Volume 12, Issue 5, Pages 2515-2525Publisher
MDPI AG
DOI: 10.3390/md12052515
Keywords
antioxidant; Avicennia marina; chlorocornoside; cornoside; jacaranone analogs; marinoid
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Funding
- National Natural Science Foundation of China [31100260, 81260480, 81260673, 81060344]
- Knowledge Innovation Program of Chinese Academy of Sciences [KSCX2-EW-J-28]
- Natural Science Foundation of Guangxi [2011GXNSFE018002, 2011GXNSFB018035, 2011GXNSFA018108, 2012GXNSFAA053160, 2012GXNSFEA053001]
- CAS
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Four new jacaranone analogs, marinoids F-I (1-4), were isolated from the fruits of a Beibu Gulf mangrove Avicennia marina. The structures were elucidated based on analysis of spectroscopic data. Marinoids F and G are shown to be diastereoisomers of chlorocornoside, a new halogen containing marine secondary metabolite. The antioxidant activity of the isolates was evaluated using a cellular antioxidant assay, and 4 showed good antioxidant activity (EC50 = 26 mu M).
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