Journal
MARINE DRUGS
Volume 12, Issue 10, Pages 5188-5196Publisher
MDPI
DOI: 10.3390/md12105188
Keywords
Zoanthus; zoanthamine alkaloids; marine natural products
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Funding
- EU [FP7-KBBE-3-245137-MAREX, FP7-REGPOT-2012-CT2012-31637-IMBRAIN]
- MINECO (Ministerio de Economia y Competitividad), Spain [SAF2011-28883-C03-01]
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Three new norzoanthamine-type alkaloids, named 2-hydroxy-11-ketonorzoan thamide B (1), norzoanthamide B (2) and 15-hydroxynorzoanthamine (3), were isolated from Zoanthus sp. specimens collected at the Canary Islands. Their structures were determined by interpretation of NMR and HR-ESIMS data. Relative configurations of their chiral centers were proposed on the basis of ROESY spectra and by comparison of their spectroscopic data with those of the well-known compound, norzoanthamine.
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