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Anticancer and Cancer Preventive Properties of Marine Polysaccharides: Some Results and Prospects

Journal

MARINE DRUGS
Volume 11, Issue 12, Pages 4876-4901

Publisher

MDPI
DOI: 10.3390/md11124876

Keywords

marine organisms; polysaccharides; anticancer; chemoprevention; anticarcinogenic; mechanisms of action

Funding

  1. Program of the Presidium of RAS Molecular and Cell Biology [12-IP6-11]
  2. RFBR [13-03-00986]
  3. Grant of President of Russia [546.2012.4]

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Many marine-derived polysaccharides and their analogues have been reported as showing anticancer and cancer preventive properties. These compounds demonstrate interesting activities and special modes of action, differing from each other in both structure and toxicity profile. Herein, literature data concerning anticancer and cancer preventive marine polysaccharides are reviewed. The structural diversity, the biological activities, and the molecular mechanisms of their action are discussed.

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