Journal
MARINE DRUGS
Volume 10, Issue 3, Pages 598-603Publisher
MDPI AG
DOI: 10.3390/md10030598
Keywords
marine endophyte; secondary metabolite; Scyphiphora hydrophyllacea; R-3-hydroxyundecanoic acid methylester-3-O-alpha-L-rhamnopyranoside
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Funding
- National Natural Science Foundation of China [20862020]
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To study the antimicrobial components from the endophytic fungus A1 of mangrove plant Scyphiphora hydrophyllacea Gaertn. F., a new fatty acid glucoside was isolated by column chromatography from the broth of A1, and its structure was identified as R-3-hydroxyundecanoic acid methylester-3-O-alpha-L-rhamnopyranoside(1) by spectroscopic methods including 1D and 2D NMR (HMQC, H-1-H-1 COSY and HMBC) and chemical methods. Antimicrobial assay showed compound 1 possessed modest inhibitory effect on Saphylococcus aureus and methicillin-resistant S. aureus (MRSA) using the filter paper disc agar diffusion method.
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